22 Results for "

Brucea antidysenterica J.F.Mill.

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "Brucea antidysenterica J.F.Mill." in MCE Product Catalog:

Yadanziolide A
Yadanziolide A
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Cat. No.: HY-N4210
CAS No.: 95258-14-3
Category:  

Infection Simaroubaceae Terpenoids Diterpenoids Plants Disease Research Fields Brucea javanica (L.) Merr.

Target:  

TMV

Yadanziolide A, isolated from the cultivated dry seeds of Brucea javanica, has strong antiviral activities with IC50 of 5.5 μM against tobacco mosaic virus. Yadanziolide A shows significant antitumor effects .
Bruceantinol
Bruceantinol
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Cat. No.: HY-N8146
CAS No.: 53729-52-5
Category:  

Infection Triterpenes Simaroubaceae Brucea antidysenterica J.F.Mill. Terpenoids Plants Disease Research Fields Cancer Brucea javanica (L.) Merr.

Target:  

STAT Bcl-2 Family Ser/Thr Kinase Survivin c-Myc Apoptosis Necroptosis CDK

Bruceantinol is a quassinoid that can be isolated from Brucea javanica, inhibits pepper mottle virus (PepMoV) in pepper. Bruceantinol is a STAT3 inhibitor demonstrating potent antitumor activity in in vitro and in vivo human colorectal cancer (CRC) models. Bruceantinol has potent anti-leukemic activity. Bruceantinol strongly inhibits STAT3 DNA-binding ability (IC50 = 2.4 pM), blocks the constitutive and IL-6-induced STAT3 activation, and suppresses transcription of MCL-1, PTTG1, survivin and c-Myc. Bruceantinol binds with CDK2/4/6 to facilitate protein degradation through proteasome pathway. Bruceantinol can dose- and time-dependently reduces the cell growth, impede cell proliferation, disrupts the cell cycle, and induces necrosis in MCF-7 cells and apoptosis in MDA-MB-231 cells .
Bruceine E
Bruceine E
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Cat. No.: HY-N3015
CAS No.: 21586-90-3
Category:  

Simaroubaceae Terpenoids Metabolic Disease Diterpenoids Plants Disease Research Fields Brucea javanica (L.) Merr.

Target:  

Others

Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect . Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ (HY-13753))-induced diabetic rats at lower dose .
Dehydrobruceine B
Dehydrobruceine B
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Cat. No.: HY-N10313
CAS No.: 53730-90-8
Category:  

Natural Products Microorganisms

Target:  

Bcl-2 Family Keap1-Nrf2 Apoptosis

Dehydrobruceine B, a quassinoid, can be isolated from Brucea javanica. Dehydrobruceine B shows a synergistic effect with Cisplatin (HY-17394) to induce apoptosis via mitochondrial method. Dehydrobruceine B increases apoptosis-inducing factor (AIF) and Bax expression and suppresses Keap1-Nrf2 .
Yadanzioside A
Yadanzioside A
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Cat. No.: HY-N4257
CAS No.: 95258-15-4
Category:  

Simaroubaceae Terpenoids Diterpenoids Plants Disease Research Fields Cancer Brucea javanica (L.) Merr.

Target:  

Others

Yadanziolide A, a quassinoid glycoside from Brucea javanica, has antitumor activity .
10-Hydroxycanthin-6-one
10-Hydroxycanthin-6-one
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Cat. No.: HY-N7153
CAS No.: 86293-41-6
Category:  

Pyridine Alkaloids Plants Indole Alkaloids Alkaloids Simaroubaceae Monophenols Phenols Disease Research Fields Cancer Brucea javanica (L.) Merr.

Target:  

Others

10-Hydroxycanthin-6-one is an antileukemic canthin-6-one alkaloid from Brucea antidysenterica. Antitumor agent .
Yadanzioside P
Yadanzioside P
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Cat. No.: HY-125067
CAS No.: 79439-84-2
Category:  

Simaroubaceae Plants Saccharides Brucea javanica (L.) Merr. Monosaccharides

Target:  

Others

Yadanzioside P is an antileukemic quassinoid glycoside. Yadanzioside P can be isolated from the seeds of Brucea javanica (L.). Yadanzioside P can be used for the research of cancer .
Bruceantarin
Bruceantarin
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Cat. No.: HY-N10591
CAS No.: 41451-76-7
Category:  

Natural Products Simaroubaceae Plants Brucea javanica (L.) Merr.

Target:  

Others

Bruceantarin is a potent antineoplastic agent. Bruceantarin can be used for leukemia and breast cancer research .
Kurchessine
Kurchessine
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Cat. No.: HY-123252
CAS No.: 6869-45-0
Synonyms: Sarcodinine
Category:  

Apocynaceae Alkaloids Steroid Alkaloids Plants Holarrhena antidysenterica Roth

Target:  

Others

Kurchessine (Sarcodinine) is an alkaloid that can be isolated from the stem bark of Holarrhena antidysenterica .
Yadanzioside F
Yadanzioside F
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Cat. No.: HY-N7190
CAS No.: 95258-11-0
Category:  

Simaroubaceae Ketones, Aldehydes, Acids Plants Disease Research Fields Cancer Brucea javanica (L.) Merr.

Target:  

Parasite

Yadanzioside F is one of the toxic components found in Brucea javanica . Brucea javanica has demonstrated a variety of antitumoral, antimalarial, and anti-inflammatory properties .
Yadanzioside K
Yadanzioside K
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Cat. No.: HY-133096
CAS No.: 101559-98-2
Category:  

Triterpenes Simaroubaceae Terpenoids Other Diseases Plants Disease Research Fields Brucea javanica (L.) Merr.

Target:  

Others

Yadanzioside K is a natural quassinoid glucoside found in Brucea amarissima .
Dehydrobruceantinol
Dehydrobruceantinol
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Cat. No.: HY-135421
CAS No.: 99132-99-7
Category:  

Triterpenes Simaroubaceae Terpenoids Plants Brucea javanica (L.) Merr.

Target:  

Others

Dehydrobruceantinol is a natural product that can be isolated from Brucea javanica .
Yadanzioside C
Yadanzioside C
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Cat. No.: HY-N7189
CAS No.: 95258-16-5
Category:  

Simaroubaceae Ketones, Aldehydes, Acids Plants Disease Research Fields Cancer Brucea javanica (L.) Merr.

Target:  

Others

Yadanzioside C is a quassinoid glucoside found in seeds of Brucea amarissima .
Bruceantinol A
Bruceantinol A
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Cat. No.: HY-N10897
CAS No.: 948038-36-6
Category:  

Simaroubaceae Terpenoids Diterpenoids Plants Brucea javanica (L.) Merr.

Target:  

Others

Bruceantinol A, a natural compound, can be isolated from Brucea javanica seeds .
Bruceantinoside A
Bruceantinoside A
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Cat. No.: HY-N9027
CAS No.: 79439-85-3
Category:  

Simaroubaceae Terpenoids Diterpenoids Plants Brucea javanica (L.) Merr.

Target:  

Others

Bruceantinoside A is a Diterpenoids product that can be isolated from the fruits of Brucea javanica. .
Bruceanic acid D
Bruceanic acid D
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Cat. No.: HY-N18086
CAS No.: 132587-61-2
Category:  

Microorganisms Terpenoids Diterpenoids

Target:  

Others

Bruceanic acid D is a quassinoid compound and cytotoxic agent that can be isolated from the xylem powder of Brucea antidysenterica. Bruceanic acid D specifically inhibits P-388 lymphocytic leukemia cells but shows no activity against human lung cancer cells and human colon cancer cells. Bruceanic acid D can be used in studies related to P-388 lymphocytic leukemia .
Dehydrobrusatol
Dehydrobrusatol
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Cat. No.: HY-N17946
CAS No.: 99132-98-6
Category:  

Simaroubaceae Terpenoids Diterpenoids Plants Brucea javanica (L.) Merr.

Target:  

Others

Dehydrobrusatol is a quassinoid found in the seeds of Brucea javanica (L.) MERR .
Bruceanol A
Bruceanol A
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Cat. No.: HY-N18237
CAS No.: 101391-06-4
Category:  

Triterpenes Simaroubaceae Brucea antidysenterica J.F.Mill. Terpenoids Plants

Target:  

Others

Bruceanol A is an antileukemic quassinoid glycoside isolated from Brucea javanica. Bruceanol A exhibits antileukemic activity against P-388 lymphocytic leukemia in vivo. Bruceanol A can be used in studies related to P-388 lymphocytic leukemia .
Isoconessimine
Isoconessimine
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Cat. No.: HY-N19482
CAS No.: 468-36-0
Category:  

Apocynaceae Alkaloids Pyrrole Alkaloids Holarrhena antidysenteriaca Plants Steroids

Target:  

Cholinesterase (ChE)

Isoconessimine is a steroidal alkaloid that can be found in the seeds of Holarrhena antidysenterica, and the IC50 value of its acetylcholinesterase inhibitory activity is > 300 μM .
Isoconessimine TFA
Isoconessimine TFA
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Cat. No.: HY-N19482A
Target:  

Cholinesterase (ChE)

Research Areas:  

Others

Isoconessimine TFA is a steroidal alkaloid that can be found in the seeds of Holarrhena antidysenterica, and the IC50 value of its acetylcholinesterase inhibitory activity is > 300 μM .
Assay Types